InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Igfals

Summary

InnateDB Protein

IDBP-149538.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Igfals

Protein Name

insulin-like growth factor binding protein, acid labile subunit

Synonyms

Albs; ALS; mKIAA4111;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000060169

InnateDB Gene

IDBG-149536 (Igfals)

Protein Structure

UniProt Annotation

Function

May have an important role in regulating the access of circulating IGFs to the tissues.

Subcellular Localization

Secreted, extracellular space.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0007155

cell adhesion

Cellular Component

GO:0005615	extracellular space
GO:0005634	nucleus
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:107973

InterPro

IPR000372 Leucine-rich repeat-containing N-terminal
IPR000483 Cysteine-rich flanking region, C-terminal
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype

PFAM

PF01462
PF01463
PF00560
PF13504
PF13855

PRINTS

PIRSF

SMART

SM00013
SM00082
SM00369

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P70389