InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Vps37a

Summary

InnateDB Protein

IDBP-149881.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Vps37a

Protein Name

vacuolar protein sorting 37A (yeast)

Synonyms

2210018P21Rik; 4930592A21Rik; AW261445; D8Ertd531e;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000096415

InnateDB Gene

IDBG-149879 (Vps37a)

Protein Structure

UniProt Annotation

Function

Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation (By similarity). {ECO:0000250}.

Subcellular Localization

Late endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0015031	protein transport
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Cellular Component

GO:0000813	ESCRT I complex
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0031902	late endosome membrane
GO:0043231	intracellular membrane-bounded organelle