InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Hepacam

Summary

InnateDB Protein

IDBP-150036.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Hepacam

Protein Name

hepatocyte cell adhesion molecule

Synonyms

2900042E01Rik; Hepn1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000054105

InnateDB Gene

IDBG-150034 (Hepacam)

Protein Structure

UniProt Annotation

Function

Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation (By similarity). {ECO:0000250UniProtKB:Q14CZ8}.

Subcellular Localization

Cytoplasm. Membrane {ECO:0000250}; Single- pass type I membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250UniProtKB:Q14CZ8}. Note=Colocalizes with CDH1. {ECO:0000250UniProtKB:Q14CZ8}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0007050	cell cycle arrest
GO:0007155	cell adhesion
GO:0034613	cellular protein localization
GO:0040008	regulation of growth

Cellular Component

GO:0005737	cytoplasm
GO:0005911	cell-cell junction
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030424	axon

Protein Structure and Domains

PDB ID

MGI:1920177

InterPro

IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin

PFAM

PF07679
PF07686
PF00047

PRINTS

PIRSF

SMART

SM00408
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q640R3