InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Il1rap

Summary

InnateDB Protein

IDBP-150441.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Il1rap

Protein Name

interleukin 1 receptor accessory protein

Synonyms

6430709H04Rik; AI255955; AV239853; IL-1RAcP;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000093843

InnateDB Gene

IDBG-150439 (Il1rap)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Experimentally validated
Total	12 [view]
Protein-Protein	12 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0004908	interleukin-1 receptor activity
GO:0005515	protein binding

Biological Process

GO:0007165	signal transduction
GO:0019221	cytokine-mediated signaling pathway
GO:0042094	interleukin-2 biosynthetic process
GO:0045087	innate immune response (InnateDB)

Cellular Component

GO:0016020

membrane

Protein Structure and Domains

PDB ID

MGI:104975

InterPro

IPR000157 Toll/interleukin-1 receptor homology (TIR) domain
IPR003599 Immunoglobulin subtype
IPR004074 Interleukin-1 receptor type I/II
IPR007110 Immunoglobulin-like domain

PFAM

PF01582
PF13676

PRINTS

PR01536

PIRSF

SMART

SM00255
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt