Version 5.4
Mus musculus Protein: Gpx2
Summary
InnateDB Protein IDBP-151267.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gpx2
Protein Name glutathione peroxidase 2
Synonyms GI-GPx; GPx-GI; GSHPx-2; GSHPx-GI;
Species Mus musculus
Ensembl Protein ENSMUSP00000081012
InnateDB Gene IDBG-151265 (Gpx2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004602 glutathione peroxidase activity
Biological Process
GO:0001659 temperature homeostasis
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0006979 response to oxidative stress
GO:0009609 response to symbiotic bacterium
GO:0051702 interaction with symbiont
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:106609
InterPro IPR000889 Glutathione peroxidase
IPR012336 Thioredoxin-like fold
PFAM PF00255
PF13098
PF13192
PF13462
PF13905
PRINTS PR01011
PIRSF PIRSF000303
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9JHC0
PhosphoSite PhosphoSite-Q9JHC0
TrEMBL
UniProt Splice Variant
Entrez Gene 14776
UniGene Mm.57225
RefSeq NP_109602
MGI ID
MGI Symbol Gpx2
OMIM
CCDS CCDS25996
HPRD
IMGT
EMBL AK131940 BC010823 BC034335 BC039658 BC054848 U62658
GenPept AAD41533 AAH10823 AAH34335 AAH39658 AAH54848 BAE20886

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca