InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Relb

Summary

InnateDB Protein

IDBP-151421.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Relb

Protein Name

avian reticuloendotheliosis viral (v-rel) oncogene related B

Synonyms

shep;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000050166

InnateDB Gene

IDBG-151419 (Relb)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 38 experimentally validated interaction(s) in this database.
They are also associated with 113 interaction(s) predicted by orthology.

Experimentally validated
Total	39 [view]
Protein-Protein	18 [view]
Protein-DNA	20 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	1 [view]
DNA-RNA	0

Predicted by orthology
Total	113 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0010628	positive regulation of gene expression
GO:0019882	antigen processing and presentation
GO:0038061	NIK/NF-kappaB signaling
GO:0042088	T-helper 1 type immune response
GO:0043011	myeloid dendritic cell differentiation
GO:0045063	T-helper 1 cell differentiation
GO:0045087	innate immune response (InnateDB)

Cellular Component

GO:0005634	nucleus
GO:0005829	cytosol

Protein Structure and Domains

PDB ID

MGI:103289

InterPro

IPR000451 NF-kappa-B/Rel/Dorsal
IPR002909 IPT domain
IPR008967 p53-like transcription factor, DNA-binding
IPR011539 Rel homology domain
IPR014756 Immunoglobulin E-set

PFAM

PF01833
PF00554

PRINTS

PR00057

PIRSF

SMART

SM00429

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt