Version 5.4
Mus musculus Protein: Opa1
Summary
InnateDB Protein IDBP-151470.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Opa1
Protein Name optic atrophy 1 homolog (human)
Synonyms 1200011N24Rik; AI225888; AI847218; lilr3; mKIAA0567;
Species Mus musculus
Ensembl Protein ENSMUSP00000036993
InnateDB Gene IDBG-151468 (Opa1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0001843 neural tube closure
GO:0006184 GTP catabolic process
GO:0007005 mitochondrion organization
GO:0007007 inner mitochondrial membrane organization
GO:0007601 visual perception
GO:0008053 mitochondrial fusion
GO:0090201 negative regulation of release of cytochrome c from mitochondria
GO:0090398 cellular senescence
Cellular Component
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005743 mitochondrial inner membrane
GO:0030061 mitochondrial crista
Protein Structure and Domains
PDB ID MGI:1921393
InterPro IPR001401 Dynamin, GTPase domain
IPR022812 Dynamin superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00350
PRINTS PR00195
PIRSF
SMART SM00053
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H7BX01
UniProt Splice Variant
Entrez Gene 74143
UniGene Mm.421980
RefSeq NP_001186106
MGI ID
MGI Symbol Opa1
OMIM
CCDS CCDS57024
HPRD
IMGT
EMBL AC154438
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca