InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pde6a

Summary

InnateDB Protein

IDBP-151655.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pde6a

Protein Name

phosphodiesterase 6A, cGMP-specific, rod, alpha

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000025468

InnateDB Gene

IDBG-151653 (Pde6a)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0005515	protein binding
GO:0046872	metal ion binding
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity

Biological Process

GO:0007165	signal transduction
GO:0046037	GMP metabolic process
GO:0051480	cytosolic calcium ion homeostasis
GO:0060041	retina development in camera-type eye

Cellular Component

Protein Structure and Domains

PDB ID

MGI:97524

InterPro

IPR002073 3\'5\'-cyclic nucleotide phosphodiesterase, catalytic domain
IPR003018 GAF domain
IPR003607 HD/PDEase domain
IPR023088 3\'5\'-cyclic nucleotide phosphodiesterase
IPR029016 GAF domain-like

PFAM

PF00233
PF01590
PF13185
PF13492

PRINTS

PR00387

PIRSF

SMART

SM00065
SM00471

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt