Version 5.4
Mus musculus Protein: Fcnb
Summary
InnateDB Protein IDBP-151719.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fcnb
Protein Name ficolin B
Synonyms Fcn2;
Species Mus musculus
Ensembl Protein ENSMUSP00000028179
InnateDB Gene IDBG-151717 (Fcnb)
Protein Structure
UniProt Annotation
Function May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin (By similarity). {ECO:0000250}.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0033691 sialic acid binding
GO:0097367 carbohydrate derivative binding
Biological Process
GO:0001867 complement activation, lectin pathway
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005576 extracellular region
GO:0005581 collagen trimer
Protein Structure and Domains
PDB ID MGI:1341158
InterPro IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
IPR008160 Collagen triple helix repeat
PFAM PF00147
PF01391
PRINTS
PIRSF
SMART SM00186
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O70497
PhosphoSite PhosphoSite-O70497
TrEMBL
UniProt Splice Variant
Entrez Gene 14134
UniGene Mm.182935
RefSeq NP_034320
MGI ID
MGI Symbol Fcnb
OMIM
CCDS CCDS15832
HPRD
IMGT
EMBL AF063217 BC107220 BC107221
GenPept AAC98781 AAI07221 AAI07222

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca