Mus musculus Protein: Mtnr1a | |||||||||||||
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Summary | |||||||||||||
InnateDB Protein | IDBP-152016.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | Mtnr1a | ||||||||||||
Protein Name | melatonin receptor 1A | ||||||||||||
Synonyms | MelR; MR; | ||||||||||||
Species | Mus musculus | ||||||||||||
Ensembl Protein | ENSMUSP00000069872 | ||||||||||||
InnateDB Gene | IDBG-152014 (Mtnr1a) | ||||||||||||
Protein Structure | |||||||||||||
UniProt Annotation | |||||||||||||
Function | High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity (By similarity). {ECO:0000250}. | ||||||||||||
Subcellular Localization | Cell membrane; Multi-pass membrane protein. | ||||||||||||
Disease Associations | |||||||||||||
Tissue Specificity | |||||||||||||
Comments | |||||||||||||
Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||||
PDB ID | MGI:102967 | ||||||||||||
InterPro |
IPR000025
Melatonin receptor family IPR000276 G protein-coupled receptor, rhodopsin-like IPR000611 Neuropeptide Y receptor family IPR002278 Melatonin receptor 1A IPR002279 Melatonin receptor type 1C IPR017452 GPCR, rhodopsin-like, 7TM IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx IPR019430 7TM GPCR, serpentine receptor class x (Srx) |
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PFAM |
PF00001
PF10320 PF10328 |
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PRINTS |
PR00857
PR00237 PR01012 PR01149 PR01150 |
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PIRSF | |||||||||||||
SMART | |||||||||||||
TIGRFAMs | |||||||||||||
Post-translational Modifications | |||||||||||||
Modification | |||||||||||||
Cross-References | |||||||||||||
SwissProt | Q61184 | ||||||||||||
PhosphoSite | PhosphoSite-Q61184 | ||||||||||||
TrEMBL | Q14AC3 | ||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 17773 | ||||||||||||
UniGene | Mm.5133 | ||||||||||||
RefSeq | NP_032665 | ||||||||||||
MGI ID | |||||||||||||
MGI Symbol | Mtnr1a | ||||||||||||
OMIM | |||||||||||||
CCDS | CCDS22273 | ||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | BC116900 BC119313 CH466554 U52222 | ||||||||||||
GenPept | AAB08755 AAI16901 AAI19314 EDL35540 | ||||||||||||