Version 5.4
Mus musculus Protein: Sdpr
Summary
InnateDB Protein IDBP-152389.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sdpr
Protein Name serum deprivation response
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000055694
InnateDB Gene IDBG-152387 (Sdpr)
Protein Structure
UniProt Annotation
Function May play a role in targeting PRKCA to caveolae. {ECO:0000250UniProtKB:Q66H98}.
Subcellular Localization Cytoplasm, cytosol {ECO:0000269PubMed:18332105}. Membrane, caveola {ECO:0000250}. Note=Colocalizes with CAV1 to caveolae. {ECO:0000250}.
Disease Associations
Tissue Specificity Highly expressed in kidney, lung and heart, and expressed at lower levels in liver, spleen, thymus, stomach, intestine and uterus. {ECO:0000269PubMed:8241023}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001786 phosphatidylserine binding
GO:0005515 protein binding
Biological Process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005901 caveola
Protein Structure and Domains
PDB ID MGI:99513
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q63918
PhosphoSite PhosphoSite-Q63918
TrEMBL
UniProt Splice Variant
Entrez Gene 20324
UniGene Mm.490590
RefSeq NP_620080
MGI ID
MGI Symbol Sdpr
OMIM
CCDS CCDS14940
HPRD
IMGT
EMBL AK035324 AK084096 AK132324 BC020008 BC027005 S67386
GenPept AAB28953 AAH20008 AAH27005 BAC29033 BAC39116 BAE21104

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca