Version 5.4
Mus musculus Gene: Sdpr
Summary
InnateDB Gene IDBG-152387.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sdpr
Gene Name serum deprivation response
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000045954
Encoded Proteins
IDBP-152389
serum deprivation response
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168497:
This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.[provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:51289126-51302960
Strand Forward strand
Band C1.1
Transcripts
ENSMUST00000051572 ENSMUSP00000055694
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001786 phosphatidylserine binding
GO:0005515 protein binding
Biological Process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005901 caveola
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000168497
View Gene Order
ENSBTAG00000018497
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q63918
TrEMBL
UniProt Splice Variant
Entrez Gene 20324
UniGene Mm.398690 Mm.490590
RefSeq NM_138741
OMIM
CCDS CCDS14940
HPRD
IMGT
MGI ID MGI:99513
MGI Symbol Sdpr
EMBL AK035324 AK084096 AK132324 BC020008 BC027005 S67386
GenPept AAB28953 AAH20008 AAH27005 BAC29033 BAC39116 BAE21104
RNA Seq Atlas 20324

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca