InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rab1

Summary

InnateDB Protein

IDBP-152609.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Rab1

Protein Name

RAB1, member RAS oncogene family

Synonyms

Gtbp; mKIAA3012; Rab-1; Rab1A; Ypt1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000020358

InnateDB Gene

IDBG-152605 (Rab1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	40 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005525	GTP binding

Biological Process

GO:0000045	autophagic vacuole assembly
GO:0006184	GTP catabolic process
GO:0006886	intracellular protein transport
GO:0006888	ER to Golgi vesicle-mediated transport
GO:0006897	endocytosis
GO:0006913	nucleocytoplasmic transport
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0015031	protein transport
GO:0016477	cell migration
GO:0030252	growth hormone secretion
GO:0042742	defense response to bacterium
GO:0047496	vesicle transport along microtubule
GO:0072606	interleukin-8 secretion

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0016020	membrane

Protein Structure and Domains

PDB ID

MGI:97842

InterPro

IPR000795 Elongation factor, GTP-binding domain
IPR001806 Small GTPase superfamily
IPR002041 Ran GTPase
IPR003578 Small GTPase superfamily, Rho type
IPR003579 Small GTPase superfamily, Rab type
IPR005225 Small GTP-binding protein domain
IPR006689 Small GTPase superfamily, ARF/SAR type
IPR006762 Gtr1/RagA G protein
IPR013684 Mitochondrial Rho-like
IPR019009 Signal recognition particle receptor, beta subunit
IPR020849 Small GTPase superfamily, Ras type
IPR024156 Small GTPase superfamily, ARF type
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00009
PF00071
PF00025
PF04670
PF08477
PF09439

PRINTS

PR00315
PR00449
PR00627
PR00328

PIRSF

SMART

SM00176
SM00174
SM00175
SM00173
SM00177

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q5SW88

UniProt Splice Variant

Entrez Gene

19324

UniGene

Mm.491009

RefSeq

MGI ID

MGI Symbol

Rab1

OMIM

CCDS

HPRD

IMGT

EMBL

AL606522

GenPept