InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Rab1

Summary

InnateDB Gene

IDBG-152605.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rab1

Gene Name

RAB1, member RAS oncogene family

Synonyms

Gtbp; mKIAA3012; Rab-1; Rab1A; Ypt1

Species

Mus musculus

Ensembl Gene

ENSMUSG00000020149

Encoded Proteins

IDBP-152609

RAB1, member RAS oncogene family

IDBP-262040

RAB1, member RAS oncogene family

IDBP-262042

RAB1, member RAS oncogene family

IDBP-627133

RAB1, member RAS oncogene family

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138069:
This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms. [provided by RefSeq, Oct 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:20201432-20226856

Strand

Forward strand

Band

A3.1

Transcripts

ENSMUST00000020358	ENSMUSP00000020358
ENSMUST00000109602	ENSMUSP00000105231
ENSMUST00000109601	ENSMUSP00000105230
ENSMUST00000132285
ENSMUST00000152728
ENSMUST00000163483	ENSMUSP00000127330

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	40 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005515	protein binding
GO:0005525	GTP binding

Biological Process

GO:0000045	autophagic vacuole assembly
GO:0006184	GTP catabolic process
GO:0006886	intracellular protein transport
GO:0006888	ER to Golgi vesicle-mediated transport
GO:0006897	endocytosis
GO:0006913	nucleocytoplasmic transport
GO:0006914	autophagy
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0015031	protein transport
GO:0016477	cell migration
GO:0030252	growth hormone secretion
GO:0032402	melanosome transport
GO:0034446	substrate adhesion-dependent cell spreading
GO:0042742	defense response to bacterium
GO:0047496	vesicle transport along microtubule
GO:0072606	interleukin-8 secretion

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005769	early endosome
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0005829	cytosol
GO:0016020	membrane
GO:0042470	melanosome
GO:0070062	extracellular vesicular exosome