Version 5.4
Mus musculus Protein: Pdlim3
Summary
InnateDB Protein IDBP-153236.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pdlim3
Protein Name PDZ and LIM domain 3
Synonyms Actn2lp; AI463105; ALP;
Species Mus musculus
Ensembl Protein ENSMUSP00000034053
InnateDB Gene IDBG-153234 (Pdlim3)
Protein Structure
UniProt Annotation
Function May play a role in the organization of actin filament arrays within muscle cells. {ECO:0000250}.
Subcellular Localization Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}. Note=Localizes to myofiber Z-lines. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008092 cytoskeletal protein binding
GO:0008270 zinc ion binding
GO:0008307 structural constituent of muscle
Biological Process
GO:0007015 actin filament organization
GO:0007507 heart development
Cellular Component
GO:0005737 cytoplasm
GO:0015629 actin cytoskeleton
GO:0030018 Z disc
Protein Structure and Domains
PDB ID MGI:1859274
InterPro IPR001478 PDZ domain
IPR001781 Zinc finger, LIM-type
IPR006643 ZASP
PFAM PF00595
PF13180
PF00412
PRINTS
PIRSF
SMART SM00228
SM00132
SM00735
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O70209
PhosphoSite PhosphoSite-O70209
TrEMBL
UniProt Splice Variant
Entrez Gene 53318
UniGene
RefSeq NP_058078
MGI ID 1X64
MGI Symbol Pdlim3
OMIM
CCDS CCDS22281
HPRD
IMGT
EMBL AF002283 AK078421 BC070418
GenPept AAC16673 AAH70418 BAC37266

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca