InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Hrh2

Summary

InnateDB Protein

IDBP-153385.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Hrh2

Protein Name

histamine receptor H2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000038170

InnateDB Gene

IDBG-153383 (Hrh2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0004969	histamine receptor activity

Biological Process

GO:0001696	gastric acid secretion
GO:0001697	histamine-induced gastric acid secretion
GO:0001698	gastrin-induced gastric acid secretion
GO:0003382	epithelial cell morphogenesis
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007613	memory
GO:0008542	visual learning
GO:0045907	positive regulation of vasoconstriction
GO:0048167	regulation of synaptic plasticity
GO:0048565	digestive tract development
GO:0048732	gland development

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:108482

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000503 Histamine H2 receptor
IPR002233 Adrenoceptor family
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx

PFAM

PF00001
PF10320

PRINTS

PR00237
PR00531
PR01103

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P97292