Version 5.4
Mus musculus Protein: Ugp2
Summary
InnateDB Protein IDBP-153411.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ugp2
Protein Name UDP-glucose pyrophosphorylase 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000056324
InnateDB Gene IDBG-153407 (Ugp2)
Protein Structure
UniProt Annotation
Function Plays a central role as a glucosyl donor in cellular metabolic pathways.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity
GO:0005536 glucose binding
GO:0016779 nucleotidyltransferase activity
GO:0032557 pyrimidine ribonucleotide binding
GO:0046872 metal ion binding
Biological Process
GO:0006011 UDP-glucose metabolic process
GO:0008152 metabolic process
GO:0019255 glucose 1-phosphate metabolic process
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:2183447
InterPro IPR002618 UTP--glucose-1-phosphate uridylyltransferase
IPR016267 UTP--glucose-1-phosphate uridylyltransferase, subgroup
IPR029044 Nucleotide-diphospho-sugar transferases
PFAM PF01704
PRINTS
PIRSF PIRSF000806
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q91ZJ5
PhosphoSite PhosphoSite-Q91ZJ5
TrEMBL Q8R0M2
UniProt Splice Variant
Entrez Gene 216558
UniGene Mm.28877
RefSeq NP_001277563
MGI ID
MGI Symbol Ugp2
OMIM
CCDS CCDS70148
HPRD
IMGT
EMBL AF424698 AK033445 AK153885 AL772195 AL833772 BC023810 BC025585 BC026626 BC061208
GenPept AAH23810 AAH25585 AAH26626 AAH61208 AAL24807 BAC28291 BAE32232 CAI24171 CAI24172 CAI24601 CAI24602

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca