InnateDB Protein
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IDBP-153896.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Acsl1
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Protein Name
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acyl-CoA synthetase long-chain family member 1
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Synonyms
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Acas; Acas1; Acs; Facl2; FACS; LACS1;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000034046
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InnateDB Gene
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IDBG-153894 (Acsl1)
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Protein Structure
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Function |
Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses oleate, arachidonate, eicosapentaenoate and docosahexaenoate as substrates (By similarity). {ECO:0000250}.
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Subcellular Localization |
Mitochondrion outer membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Peroxisome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Microsome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated |
Total |
13
[view]
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Protein-Protein |
13
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
4 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:102797
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InterPro |
IPR000873
AMP-dependent synthetase/ligase
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PFAM |
PF00501
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P41216
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PhosphoSite |
PhosphoSite-P41216
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TrEMBL |
D3Z457
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UniProt Splice Variant |
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Entrez Gene |
14081
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UniGene |
Mm.398595
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RefSeq |
NP_032007
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MGI ID |
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MGI Symbol |
Acsl1
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OMIM |
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CCDS |
CCDS22291
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HPRD |
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IMGT |
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EMBL |
AC138367
AK004897
AK145900
AK149406
AK152772
AK153050
AK161189
AK168078
BC056644
U15977
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GenPept |
AAA52193
AAH56644
BAB23652
BAE26736
BAE28854
BAE31484
BAE31678
BAE36230
BAE40051
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