InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tacstd2

Summary

InnateDB Protein

IDBP-154085.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tacstd2

Protein Name

tumor-associated calcium signal transducer 2

Synonyms

C80403; EGP-1; GA733-1; Ly97; TROP2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000060099

InnateDB Gene

IDBG-154083 (Tacstd2)

Protein Structure

UniProt Annotation

Function

May function as a growth factor receptor. {ECO:0000250}.

Subcellular Localization

Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Expressed in kidney, lung, ovary and testis. High levels of expression in immortalized keratinocytes. {ECO:0000269PubMed:9462726}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0010633	negative regulation of epithelial cell migration
GO:0050678	regulation of epithelial cell proliferation
GO:0051497	negative regulation of stress fiber assembly
GO:0060675	ureteric bud morphogenesis
GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis
GO:1900025	negative regulation of substrate adhesion-dependent cell spreading
GO:1900028	negative regulation of ruffle assembly
GO:2000146	negative regulation of cell motility
GO:2000738	positive regulation of stem cell differentiation

Cellular Component

GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0009925	basal plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016328	lateral plasma membrane
GO:0070062	extracellular vesicular exosome