Version 5.4
Mus musculus Gene: Tacstd2
Summary
InnateDB Gene IDBG-154083.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tacstd2
Gene Name tumor-associated calcium signal transducer 2
Synonyms C80403; EGP-1; GA733-1; Ly97; TROP2
Species Mus musculus
Ensembl Gene ENSMUSG00000051397
Encoded Proteins
IDBP-154085
tumor-associated calcium signal transducer 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184292:
This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:67534059-67535822
Strand Reverse strand
Band C1
Transcripts
ENSMUST00000058178 ENSMUSP00000060099
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0010633 negative regulation of epithelial cell migration
GO:0050678 regulation of epithelial cell proliferation
GO:0051497 negative regulation of stress fiber assembly
GO:0060675 ureteric bud morphogenesis
GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis
GO:1900025 negative regulation of substrate adhesion-dependent cell spreading
GO:1900028 negative regulation of ruffle assembly
GO:2000146 negative regulation of cell motility
GO:2000738 positive regulation of stem cell differentiation
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0009925 basal plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016328 lateral plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000184292
View Gene Order
ENSBTAG00000004381
Not yet available
Cross-References
SwissProt Q8BGV3
TrEMBL
UniProt Splice Variant
Entrez Gene 56753
UniGene Mm.439913
RefSeq NM_020047
OMIM
CCDS CCDS20221
HPRD
IMGT
MGI ID MGI:1861606
MGI Symbol Tacstd2
EMBL AK076410 AK077370 AK085753 BC117719 BC117720 CH466523 Y08830
GenPept AAI17720 AAI17721 BAC36328 BAC36773 BAC39531 CAA70063 EDK98807
RNA Seq Atlas 56753

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca