InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Arhgap4

Summary

InnateDB Protein

IDBP-154209.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Arhgap4

Protein Name

Rho GTPase activating protein 4

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000067477

InnateDB Gene

IDBG-154207 (Arhgap4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005100	Rho GTPase activator activity
GO:0005515	protein binding

Biological Process

GO:0007165	signal transduction
GO:0007399	nervous system development
GO:0010764	negative regulation of fibroblast migration
GO:0030517	negative regulation of axon extension
GO:0032321	positive regulation of Rho GTPase activity

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0005874	microtubule
GO:0005925	focal adhesion
GO:0030426	growth cone

Protein Structure and Domains

PDB ID

MGI:2159577

InterPro

IPR000198 Rho GTPase-activating protein domain
IPR001060 FCH domain
IPR001452 SH3 domain
IPR008936 Rho GTPase activation protein
IPR011511 Variant SH3 domain

PFAM

PF00620
PF00611
PF00018
PF14604
PF07653

PRINTS

PR00452

PIRSF

SMART

SM00324
SM00055
SM00326

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt