Version 5.4
Mus musculus Protein: Nme4
Summary
InnateDB Protein IDBP-154635.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nme4
Protein Name non-metastatic cells 4, protein expressed in
Synonyms 2610027N22Rik; 2810024O08Rik; 5730493H09Rik; NM23-M4; Nm23M4;
Species Mus musculus
Ensembl Protein ENSMUSP00000025007
InnateDB Gene IDBG-154633 (Nme4)
Protein Structure
UniProt Annotation
Function Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
Subcellular Localization Mitochondrion intermembrane space {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in the base region of the oxyntic and pyloric mucosae. {ECO:0000269PubMed:16476741}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004550 nucleoside diphosphate kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0032403 protein complex binding
GO:0046872 metal ion binding
Biological Process
GO:0006165 nucleoside diphosphate phosphorylation
GO:0006183 GTP biosynthetic process
GO:0006228 UTP biosynthetic process
GO:0006241 CTP biosynthetic process
Cellular Component
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space
Protein Structure and Domains
PDB ID MGI:1931148
InterPro IPR001564 Nucleoside diphosphate kinase
PFAM PF00334
PRINTS PR01243
PIRSF
SMART SM00562
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9WV84
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 56520
UniGene
RefSeq NP_062705
MGI ID
MGI Symbol Nme4
OMIM
CCDS CCDS28544
HPRD
IMGT
EMBL AF153451 AF288690 AF288692 BC027277
GenPept AAD38977 AAG02200 AAG02202 AAH27277

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca