InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Nme4

Summary

InnateDB Gene

IDBG-154633.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nme4

Gene Name

NME/NM23 nucleoside diphosphate kinase 4

Synonyms

2610027N22Rik; 2810024O08Rik; 5730493H09Rik; NM23-M4; Nm23M4

Species

Mus musculus

Ensembl Gene

ENSMUSG00000024177

Encoded Proteins

IDBP-154635

non-metastatic cells 4, protein expressed in

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000103202:
The nucleoside diphosphate (NDP) kinases (EC 2.7.4.6) are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates. The enzymes are products of the nm23 gene family, which includes NME4 (Milon et al., 1997 [PubMed 9099850]).[supplied by OMIM, May 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 17:26091734-26095508

Strand

Reverse strand

Band

A3.3

Transcripts

ENSMUST00000025007	ENSMUSP00000025007
ENSMUST00000150280

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004550	nucleoside diphosphate kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0032403	protein complex binding
GO:0046872	metal ion binding

Biological Process

GO:0006165	nucleoside diphosphate phosphorylation
GO:0006183	GTP biosynthetic process
GO:0006228	UTP biosynthetic process
GO:0006241	CTP biosynthetic process