InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gnal

Summary

InnateDB Protein

IDBP-155058.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Gnal

Protein Name

guanine nucleotide binding protein, alpha stimulating, olfactory type

Synonyms

2610011C15Rik; 9630020G10Rik; Galphaolf; Gna10; Golf;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000025402

InnateDB Gene

IDBG-155056 (Gnal)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001664	G-protein coupled receptor binding
GO:0003924	GTPase activity
GO:0004016	adenylate cyclase activity
GO:0004871	signal transducer activity
GO:0005525	GTP binding
GO:0019001	guanyl nucleotide binding
GO:0031683	G-protein beta/gamma-subunit complex binding

Biological Process

GO:0001975	response to amphetamine
GO:0006171	cAMP biosynthetic process
GO:0006184	GTP catabolic process
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007190	activation of adenylate cyclase activity
GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007608	sensory perception of smell
GO:0031000	response to caffeine

Cellular Component

GO:0005834	heterotrimeric G-protein complex
GO:0031234	extrinsic component of cytoplasmic side of plasma membrane

Protein Structure and Domains

PDB ID

MGI:95774

InterPro

IPR000367 G-protein alpha subunit, group S
IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit
IPR006689 Small GTPase superfamily, ARF/SAR type
IPR011025 G protein alpha subunit, helical insertion
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00503
PF00025

PRINTS

PR00443
PR00318
PR00328

PIRSF

SMART

SM00275

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt