InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fabp1

Summary

InnateDB Protein

IDBP-155321.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fabp1

Protein Name

fatty acid binding protein 1, liver

Synonyms

Fabpl; L-FABP;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000064655

InnateDB Gene

IDBG-155319 (Fabp1)

Protein Structure

UniProt Annotation

Function

Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. Also seems to bind selenium.

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0005324	long-chain fatty acid transporter activity
GO:0005504	fatty acid binding
GO:0005515	protein binding
GO:0005543	phospholipid binding
GO:0008144	drug binding
GO:0016209	antioxidant activity
GO:0032052	bile acid binding

Biological Process

GO:0006810	transport
GO:0008284	positive regulation of cell proliferation
GO:0015909	long-chain fatty acid transport
GO:0032000	positive regulation of fatty acid beta-oxidation
GO:0043066	negative regulation of apoptotic process
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0050892	intestinal absorption
GO:0051345	positive regulation of hydrolase activity
GO:0070301	cellular response to hydrogen peroxide
GO:0071456	cellular response to hypoxia