Version 5.4
Mus musculus Protein: Dolk
Summary
InnateDB Protein IDBP-156110.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dolk
Protein Name dolichol kinase
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000097792
InnateDB Gene IDBG-156108 (Dolk)
Protein Structure
UniProt Annotation
Function Involved in the synthesis of the sugar donor Dol-P-Man which is required in the synthesis of N-linked and O-linked oligosaccharides and for that of GPI anchors. {ECO:0000250UniProtKB:P20048}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250UniProtKB:Q9UPQ8}; Multi-pass membrane protein {ECO:0000250UniProtKB:Q9UPQ8}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004168 dolichol kinase activity
Biological Process
GO:0016310 phosphorylation
GO:0043048 dolichyl monophosphate biosynthetic process
Cellular Component
GO:0030176 integral component of endoplasmic reticulum membrane
Protein Structure and Domains
PDB ID MGI:2677836
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R2Y3
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 227697
UniGene Mm.467248
RefSeq NP_808316
MGI ID
MGI Symbol Dolk
OMIM
CCDS CCDS15877
HPRD
IMGT
EMBL AB073968 AK144705 AL954388 BC026973 CH466542
GenPept AAH26973 BAE26024 BAF82000 CAM23161 EDL08455

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca