Version 5.4
| Mus musculus Gene: Dolk | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-156108.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Dolk | ||||||
| Gene Name | dolichol kinase | ||||||
| Synonyms | |||||||
| Species | Mus musculus | ||||||
| Ensembl Gene | ENSMUSG00000075419 | ||||||
| Encoded Proteins |
dolichol kinase
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000175283:
The protein encoded by this gene catalyzes the CTP-mediated phosphorylation of dolichol, and is involved in the synthesis of Dol-P-Man, which is an essential glycosyl carrier lipid for C- and O-mannosylation, N- and O-linked glycosylation of proteins, and for the biosynthesis of glycosyl phosphatidylinositol anchors in endoplasmic reticulum. Mutations in this gene are associated with dolichol kinase deficiency.[provided by RefSeq, Apr 2010] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 2:30284231-30286334 | ||||||
| Strand | Reverse strand | ||||||
| Band | B | ||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||
| NETPATH | |||||||
| REACTOME |
Synthesis of substrates in N-glycan biosythesis pathway
Synthesis of Dolichyl-phosphate pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Asparagine N-linked glycosylation pathway
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| KEGG |
N-Glycan biosynthesis pathway
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| INOH | |||||||
| PID NCI | |||||||
| Pathway Predictions based on Human Orthology Data | |||||||
| NETPATH | |||||||
| REACTOME |
Synthesis of Dolichyl-phosphate pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Asparagine N-linked glycosylation pathway
Post-translational protein modification pathway
Synthesis of substrates in N-glycan biosythesis pathway
Metabolism of proteins pathway
Asparagine N-linked glycosylation pathway
Synthesis of Dolichyl-phosphate pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Synthesis of substrates in N-glycan biosythesis pathway
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| KEGG |
N-Glycan biosynthesis pathway
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| INOH | |||||||
| PID NCI | |||||||
| Cross-References | |||||||
| SwissProt | Q8R2Y3 | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 227697 | ||||||
| UniGene | Mm.26690 Mm.467248 | ||||||
| RefSeq | NM_177648 | ||||||
| OMIM | |||||||
| CCDS | CCDS15877 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| MGI ID | MGI:2677836 | ||||||
| MGI Symbol | Dolk | ||||||
| EMBL | AB073968 AK144705 AL954388 BC026973 CH466542 | ||||||
| GenPept | AAH26973 BAE26024 BAF82000 CAM23161 EDL08455 | ||||||
| RNA Seq Atlas | 227697 | ||||||