Version 5.4
Homo sapiens Protein: LACTB
Summary
InnateDB Protein IDBP-15613.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LACTB
Protein Name lactamase, beta
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000261893
InnateDB Gene IDBG-15609 (LACTB)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Mitochondrion {ECO:0000269PubMed:11551941, ECO:0000269PubMed:19858488}.
Disease Associations
Tissue Specificity Expressed predominantly in skeletal muscle.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 4 [view]
Protein-DNA 5 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID
InterPro IPR001466 Beta-lactamase-related
IPR012338 Beta-lactamase/transpeptidase-like
PFAM PF00144
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P83111
PhosphoSite PhosphoSite-P83111
TrEMBL H0YNN5
UniProt Splice Variant
Entrez Gene 114294
UniGene Hs.410388
RefSeq NP_116246
HUGO HGNC:16468
OMIM 608440
CCDS CCDS10182
HPRD 07466
IMGT
EMBL AC087612 AK027808 AY358709 BC067288
GenPept AAH67288 AAQ89072 BAB55384

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca