Version 5.4
Mus musculus Protein: Rfx3
Summary
InnateDB Protein IDBP-156329.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rfx3
Protein Name regulatory factor X, 3 (influences HLA class II expression)
Synonyms C230093O12Rik; MRFX3;
Species Mus musculus
Ensembl Protein ENSMUSP00000038760
InnateDB Gene IDBG-156327 (Rfx3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0044212 transcription regulatory region DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0007368 determination of left/right symmetry
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0000790 nuclear chromatin
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:106582
InterPro IPR003150 DNA-binding RFX-type winged-helix domain
IPR007668 RFX1 transcription activation region
PFAM PF02257
PF04589
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G5E890
UniProt Splice Variant
Entrez Gene 19726
UniGene Mm.394476
RefSeq
MGI ID
MGI Symbol Rfx3
OMIM
CCDS
HPRD
IMGT
EMBL AC118005 AC118628
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca