Version 5.4
Mus musculus Protein: Gab3
Summary
InnateDB Protein IDBP-156654.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gab3
Protein Name growth factor receptor bound protein 2-associated protein 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000041951
InnateDB Gene IDBG-156652 (Gab3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity Highly expressed in spleen and thymus and weakly in brain, heart, lung, kidney, uterus, and embryonic stem cells. Also expressed in myeloid and macrophage cell lines.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0030225 macrophage differentiation
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:2387324
InterPro IPR001849 Pleckstrin homology domain
PFAM PF00169
PRINTS
PIRSF
SMART SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BSM5
PhosphoSite PhosphoSite-Q8BSM5
TrEMBL B9EIZ0
UniProt Splice Variant
Entrez Gene 210710
UniGene Mm.267056
RefSeq NP_853615
MGI ID
MGI Symbol Gab3
OMIM
CCDS CCDS30235
HPRD
IMGT
EMBL AJ748654 AK031227 AL808110 AL845304 AY057988 BC141240
GenPept AAI41241 AAL25824 BAC27308 CAG38688 CAM16813 CAM26483

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca