Mus musculus Gene: Gab3
Summary
InnateDB Gene IDBG-156652.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gab3
Gene Name growth factor receptor bound protein 2-associated protein 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000032750
Encoded Proteins
growth factor receptor bound protein 2-associated protein 3
growth factor receptor bound protein 2-associated protein 3
growth factor receptor bound protein 2-associated protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160219:
This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:74966843-75085458
Strand Reverse strand
Band A7.3
Transcripts
ENSMUST00000037374 ENSMUSP00000041951
ENSMUST00000114109 ENSMUSP00000109744
ENSMUST00000114104 ENSMUSP00000109739
ENSMUST00000127024
ENSMUST00000129495
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0030225 macrophage differentiation
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.267056
RefSeq NM_181584
OMIM
CCDS CCDS30235
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas