Version 5.4
Homo sapiens Protein: DCTN6
Summary
InnateDB Protein IDBP-15712.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DCTN6
Protein Name dynactin 6
Synonyms p27; WS-3; WS3;
Species Homo sapiens
Ensembl Protein ENSP00000221114
InnateDB Gene IDBG-15710 (DCTN6)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm, cytoskeleton {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000269PubMed:23455152}.
Disease Associations
Tissue Specificity Ubiquitous.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0045502 dynein binding
Biological Process
GO:0007052 mitotic spindle organization
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
Cellular Component
GO:0000777 condensed chromosome kinetochore
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005869 dynactin complex
Protein Structure and Domains
PDB ID
InterPro IPR011004 Trimeric LpxA-like
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O00399
PhosphoSite PhosphoSite-O00399
TrEMBL
UniProt Splice Variant
Entrez Gene 10671
UniGene Hs.158427
RefSeq NP_006562
HUGO HGNC:16964
OMIM 612963
CCDS CCDS6076
HPRD 09907
IMGT
EMBL AK314128 BC013175 CH471080 CR456851 D84145
GenPept AAH13175 BAA19984 BAG36818 CAG33132 EAW63466

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca