Version 5.4
Mus musculus Protein: Cxcl14
Summary
InnateDB Protein IDBP-157152.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cxcl14
Protein Name chemokine (C-X-C motif) ligand 14
Synonyms 1110031L23Rik; 1200006I23Rik; AI414372; BMAC; bolekine; BRAK; Kec; KS1; MIP-2g; MIP2gamma; NJAC; Scyb14;
Species Mus musculus
Ensembl Protein ENSMUSP00000021970
InnateDB Gene IDBG-157150 (Cxcl14)
Protein Structure
UniProt Annotation
Function Chemotactic for CESS B-cells and THP-1 monocytes, but not T-cells. {ECO:0000269PubMed:10784614}.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity Highly expressed in brain, lung, ovary, muscle and in kidney and liver parenchyma, and at lower levels in bone marrow. {ECO:0000269PubMed:10784614, ECO:0000269PubMed:10946286}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008009 chemokine activity
Biological Process
GO:0006955 immune response
GO:0048839 inner ear development
GO:0060326 cell chemotaxis
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005794 Golgi apparatus
Protein Structure and Domains
PDB ID MGI:1888514
InterPro IPR001811 Chemokine interleukin-8-like domain
PFAM PF00048
PRINTS
PIRSF
SMART SM00199
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9WUQ5
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 57266
UniGene Mm.30211
RefSeq NP_062514
MGI ID
MGI Symbol Cxcl14
OMIM
CCDS CCDS36679
HPRD
IMGT
EMBL AB041614 AF144754 AF152377 AF192557 AF252873 AF352784 AF352785 AK004615 AK014351 AK076112 AK155356 BC147274 BC147275 CH466546
GenPept AAD34157 AAF03753 AAF65570 AAF66694 AAI47275 AAI47276 AAK52902 AAK52903 BAA95097 BAB23411 BAB29292 BAC36192 BAE33213 EDL41235

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca