Version 5.4
| Mus musculus Gene: Cxcl14 | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-157150.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Cxcl14 | ||||||
| Gene Name | chemokine (C-X-C motif) ligand 14 | ||||||
| Synonyms | 1110031L23Rik; 1200006I23Rik; AI414372; BMAC; bolekine; BRAK; Kec; KS1; MIP-2g; MIP2gamma; NJAC; Scyb14 | ||||||
| Species | Mus musculus | ||||||
| Ensembl Gene | ENSMUSG00000021508 | ||||||
| Encoded Proteins |
chemokine (C-X-C motif) ligand 14
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| InnateDB Annotation from Orthologs | |||||||
| Summary |
[Homo sapiens] CXCL14 is important for constitutive antimicrobial defences against pneumonia
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| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000145824:
This gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. [provided by RefSeq, Jul 2008] This antimicrobial gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. [provided by RefSeq, Sep 2014] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 13:56288647-56296551 | ||||||
| Strand | Reverse strand | ||||||
| Band | B1 | ||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||
| NETPATH | |||||||
| REACTOME | |||||||
| KEGG |
Cytokine-cytokine receptor interaction pathway
Chemokine signaling pathway pathway
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| INOH | |||||||
| PID NCI | |||||||
| Pathway Predictions based on Human Orthology Data | |||||||
| NETPATH | |||||||
| REACTOME | |||||||
| KEGG |
Cytokine-cytokine receptor interaction pathway
Chemokine signaling pathway pathway
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| INOH | |||||||
| PID NCI | |||||||
| Cross-References | |||||||
| SwissProt | Q9WUQ5 | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 57266 | ||||||
| UniGene | Mm.30211 | ||||||
| RefSeq | NM_019568 XM_006517308 | ||||||
| OMIM | |||||||
| CCDS | CCDS36679 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| MGI ID | MGI:1888514 | ||||||
| MGI Symbol | Cxcl14 | ||||||
| EMBL | AB041614 AF144754 AF152377 AF192557 AF252873 AF352784 AF352785 AK004615 AK014351 AK076112 AK155356 BC147274 BC147275 CH466546 | ||||||
| GenPept | AAD34157 AAF03753 AAF65570 AAF66694 AAI47275 AAI47276 AAK52902 AAK52903 BAA95097 BAB23411 BAB29292 BAC36192 BAE33213 EDL41235 | ||||||
| RNA Seq Atlas | 57266 | ||||||