Mus musculus Protein: Hnrnpa0
Summary
InnateDB Protein IDBP-157848.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hnrnpa0
Protein Name heterogeneous nuclear ribonucleoprotein A0
Synonyms 1110055B05Rik; 3010025E17Rik; hnRNP A0; Hnrpa0;
Species Mus musculus
Ensembl Protein ENSMUSP00000007980
InnateDB Gene IDBG-157846 (Hnrnpa0)
Protein Structure
UniProt Annotation
Function mRNA-binding component of ribonucleosomes. Specifically binds AU-rich element (ARE)-containing mRNAs. Involved in post- transcriptional regulation of cytokines mRNAs. {ECO:0000269PubMed:12456657}.
Subcellular Localization Nucleus {ECO:0000250}. Note=Component of ribonucleosomes. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 65 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 3 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 65 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0017091 AU-rich element binding
GO:0019901 protein kinase binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006954 inflammatory response
GO:0032496 response to lipopolysaccharide
GO:0070935 3'-UTR-mediated mRNA stabilization
Cellular Component
GO:0005634 nucleus
GO:0030529 ribonucleoprotein complex
Protein Structure and Domains
PDB ID MGI:1924384
InterPro IPR000504 RNA recognition motif domain
PFAM PF00076
PRINTS
PIRSF
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CX86
PhosphoSite PhosphoSite-Q9CX86
TrEMBL
UniProt Splice Variant
Entrez Gene 77134
UniGene Mm.490274
RefSeq NP_084148
MGI ID
MGI Symbol Hnrnpa0
OMIM
CCDS CCDS49280
HPRD
IMGT
EMBL AC165251 AK019388
GenPept BAB31694