InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Iqcb1

Summary

InnateDB Protein

IDBP-158491.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Iqcb1

Protein Name

IQ calmodulin-binding motif containing 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000023535

InnateDB Gene

IDBG-158489 (Iqcb1)

Protein Structure

UniProt Annotation

Function

Involved in ciliogenesis. {ECO:0000269PubMed:21565611}.

Subcellular Localization

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Note=Localization to the centrosome depends on the interaction with CEP290. {ECO:0000250}.

Disease Associations

Tissue Specificity

Localized to the outer segment and connecting cilia of photoreceptor cells. {ECO:0000269PubMed:15723066}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 165 experimentally validated interaction(s) in this database.
They are also associated with 166 interaction(s) predicted by orthology.

Experimentally validated
Total	165 [view]
Protein-Protein	165 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	166 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding
GO:0005516	calmodulin binding
GO:0019899	enzyme binding

Biological Process

GO:0042384	cilium assembly
GO:0045494	photoreceptor cell maintenance
GO:0048496	maintenance of organ identity

Cellular Component

GO:0001750	photoreceptor outer segment
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0015630	microtubule cytoskeleton
GO:0032391	photoreceptor connecting cilium
GO:0045171	intercellular bridge