Version 5.4
Mus musculus Protein: Cd3g
Summary
InnateDB Protein IDBP-158964.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cd3g
Protein Name CD3 antigen, gamma polypeptide
Synonyms Ctg-3; Ctg3; T3g;
Species Mus musculus
Ensembl Protein ENSMUSP00000002101
InnateDB Gene IDBG-158962 (Cd3g)
Protein Structure
UniProt Annotation
Function The CD3 complex mediates signal transduction.
Subcellular Localization Membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0005515 protein binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0007163 establishment or maintenance of cell polarity
GO:0007166 cell surface receptor signaling pathway
GO:0015031 protein transport
GO:0070228 regulation of lymphocyte apoptotic process
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0042105 alpha-beta T cell receptor complex
Protein Structure and Domains
PDB ID MGI:88333
InterPro IPR003110 Phosphorylated immunoreceptor signalling ITAM
IPR003598 Immunoglobulin subtype 2
PFAM PF02189
PRINTS
PIRSF
SMART SM00077
SM00408
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P11942
PhosphoSite PhosphoSite-P11942
TrEMBL Q3U4Y3
UniProt Splice Variant
Entrez Gene 12502
UniGene Mm.335106
RefSeq NP_033980
MGI ID 1JBJ
MGI Symbol Cd3g
OMIM
CCDS CCDS23123
HPRD
IMGT
EMBL AK153980 AK153987 BC027528 CH466522 EF474453 GU456630 M18222 M18223 M18224 M18225 M18226 M18227 M58149 Y00635
GenPept AAA37400 AAA63289 AAH27528 ABS89006 ADD13993 BAE32293 BAE32297 CAA68667 EDL25627

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca