InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Loxl3

Summary

InnateDB Protein

IDBP-159385.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Loxl3

Protein Name

lysyl oxidase-like 3

Synonyms

Lor2; Loxl2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000000707

InnateDB Gene

IDBG-159383 (Loxl3)

Protein Structure

UniProt Annotation

Function

Functions as amine oxidases toward elastin and different types of collagens. {ECO:0000250}.

Subcellular Localization

Secreted, extracellular space {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005044	scavenger receptor activity
GO:0005507	copper ion binding
GO:0005515	protein binding
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor

Biological Process

GO:0001837	epithelial to mesenchymal transition
GO:0006898	receptor-mediated endocytosis
GO:0045892	negative regulation of transcription, DNA-templated
GO:0055114	oxidation-reduction process