Version 5.4
Mus musculus Protein: Cdc42ep1
Summary
InnateDB Protein IDBP-159970.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cdc42ep1
Protein Name CDC42 effector protein (Rho GTPase binding) 1
Synonyms 1810058K22Rik; AA980734; Borg5; CEP1; MSE55;
Species Mus musculus
Ensembl Protein ENSMUSP00000060930
InnateDB Gene IDBG-159968 (Cdc42ep1)
Protein Structure
UniProt Annotation
Function Probably involved in the organization of the actin cytoskeleton. Induced membrane extensions in fibroblasts (By similarity). {ECO:0000250}.
Subcellular Localization Endomembrane system {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007266 Rho protein signal transduction
GO:0008360 regulation of cell shape
GO:0031274 positive regulation of pseudopodium assembly
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0015629 actin cytoskeleton
Protein Structure and Domains
PDB ID MGI:1929763
InterPro IPR000095 CRIB domain
PFAM PF00786
PRINTS
PIRSF
SMART SM00285
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q91W92
PhosphoSite PhosphoSite-Q91W92
TrEMBL
UniProt Splice Variant
Entrez Gene 104445
UniGene
RefSeq NP_081495
MGI ID
MGI Symbol Cdc42ep1
OMIM
CCDS CCDS27624
HPRD
IMGT
EMBL AK007896 BC016250 BC083130
GenPept AAH16250 AAH83130 BAB25335

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca