InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Wdr1

Summary

InnateDB Protein

IDBP-160221.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Wdr1

Protein Name

WD repeat domain 1

Synonyms

Aip1; D5Wsu185e; rede;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000005234

InnateDB Gene

IDBG-160219 (Wdr1)

Protein Structure

UniProt Annotation

Function

Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection, podosome {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005515	protein binding

Biological Process

GO:0007605	sensory perception of sound
GO:0048713	regulation of oligodendrocyte differentiation

Cellular Component

GO:0002102	podosome
GO:0005737	cytoplasm
GO:0005884	actin filament
GO:0015629	actin cytoskeleton
GO:0030054	cell junction
GO:0042995	cell projection
GO:0070062	extracellular vesicular exosome