InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gcat

Summary

InnateDB Protein

IDBP-160539.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gcat

Protein Name

glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)

Synonyms

AI526977; Galnr3; Kbl;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000006544

InnateDB Gene

IDBG-160537 (Gcat)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Mitochondrion {ECO:0000250}. Nucleus {ECO:0000250}. Note=Translocates to the nucleus upon cold and osmotic stress. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008890	glycine C-acetyltransferase activity
GO:0030170	pyridoxal phosphate binding

Biological Process

GO:0008152	metabolic process
GO:0009058	biosynthetic process
GO:0019518	L-threonine catabolic process to glycine

Cellular Component

GO:0005634	nucleus
GO:0005739	mitochondrion

Protein Structure and Domains

PDB ID

MGI:1349389

InterPro

IPR000192 Aminotransferase, class V/Cysteine desulfurase
IPR004839 Aminotransferase, class I/classII
IPR011282 2-amino-3-ketobutyrate coenzyme A ligase
IPR015424 Pyridoxal phosphate-dependent transferase

PFAM

PF00266
PF00155

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O88986

PhosphoSite