Mus musculus Gene: Gcat | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-160537.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | Gcat | ||||||||||||
Gene Name | glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase) | ||||||||||||
Synonyms | AI526977; Galnr3; Kbl | ||||||||||||
Species | Mus musculus | ||||||||||||
Ensembl Gene | ENSMUSG00000006378 | ||||||||||||
Encoded Proteins |
glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)
glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)
glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100116:
The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 14. [provided by RefSeq, Jan 2010] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 15:79030874-79043558 | ||||||||||||
Strand | Forward strand | ||||||||||||
Band | E1 | ||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||
NETPATH | |||||||||||||
REACTOME | |||||||||||||
KEGG |
Glycine, serine and threonine metabolism pathway
Neuroactive ligand-receptor interaction pathway
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INOH | |||||||||||||
PID NCI | |||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||
NETPATH | |||||||||||||
REACTOME | |||||||||||||
KEGG |
Glycine, serine and threonine metabolism pathway
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INOH |
Glycine Serine metabolism pathway
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PID NCI | |||||||||||||
Cross-References | |||||||||||||
SwissProt | |||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | |||||||||||||
UniGene | Mm.237085 Mm.390805 | ||||||||||||
RefSeq | NM_001161712 NM_013847 NM_015738 | ||||||||||||
OMIM | |||||||||||||
CCDS | CCDS27630 CCDS27631 CCDS49666 | ||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
MGI ID | |||||||||||||
MGI Symbol | |||||||||||||
EMBL | |||||||||||||
GenPept | |||||||||||||
RNA Seq Atlas | |||||||||||||