InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pim1

Summary

InnateDB Protein

IDBP-160727.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pim1

Protein Name

proviral integration site 1

Synonyms

Pim-1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000024811

InnateDB Gene

IDBG-160725 (Pim1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	7 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	31 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008134	transcription factor binding
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0016773	phosphotransferase activity, alcohol group as acceptor
GO:0030145	manganese ion binding
GO:0043024	ribosomal small subunit binding

Biological Process

GO:0006468	protein phosphorylation
GO:0008283	cell proliferation
GO:0009103	lipopolysaccharide biosynthetic process
GO:0030212	hyaluronan metabolic process
GO:0031659	positive regulation of cyclin-dependent protein kinase activity involved in G1/S
GO:0043066	negative regulation of apoptotic process
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity
GO:0046777	protein autophosphorylation

Cellular Component

GO:0005737	cytoplasm
GO:0016020	membrane

Protein Structure and Domains

PDB ID

MGI:97584

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR010440 Lipopolysaccharide kinase
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714
PF06293

PRINTS

PR00109

PIRSF

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt