InnateDB Protein
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IDBP-161146.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Dguok
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Protein Name
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deoxyguanosine kinase
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Synonyms
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dGK; dGK1; dGK2; dGK3;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000014698
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InnateDB Gene
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IDBG-161142 (Dguok)
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Protein Structure
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Function |
Required for the phosphorylation of several deoxyribonucleosides and certain nucleoside analogs widely employed as antiviral and chemotherapeutic agents. {ECO:0000250}.
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Subcellular Localization |
Isoform 1: Mitochondrion.Isoform 2: Cytoplasm.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
|
Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
5 [view]
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Molecular Function |
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Biological Process |
GO:0006139
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nucleobase-containing compound metabolic process
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GO:0006468
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protein phosphorylation
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GO:0009157
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deoxyribonucleoside monophosphate biosynthetic process
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GO:0009165
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nucleotide biosynthetic process
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GO:0010977
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negative regulation of neuron projection development
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GO:0046070
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dGTP metabolic process
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GO:0046122
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purine deoxyribonucleoside metabolic process
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Cellular Component |
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PDB ID |
MGI:1351602
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InterPro |
IPR002624
Deoxynucleoside kinase
IPR027417
P-loop containing nucleoside triphosphate hydrolase
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PFAM |
PF01712
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PRINTS |
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PIRSF |
PIRSF000705
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9QX60
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PhosphoSite |
PhosphoSite-Q9QX60
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TrEMBL |
Q504N4
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UniProt Splice Variant |
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Entrez Gene |
27369
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UniGene |
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RefSeq |
NP_038792
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MGI ID |
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MGI Symbol |
Dguok
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OMIM |
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CCDS |
CCDS20279
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HPRD |
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IMGT |
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EMBL |
AC090648
AJ133749
AJ133750
AK035281
BC094920
CH466523
U90524
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GenPept |
AAF14342
AAH94920
BAC29014
CAB43121
CAB43122
EDK99082
EDK99084
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