Version 5.4
Mus musculus Protein: Bst1
Summary
InnateDB Protein IDBP-161387.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bst1
Protein Name bone marrow stromal cell antigen 1
Synonyms 114/A10; A530073F09; BP-3; Bp3; Bsta1; CD157; Ly65;
Species Mus musculus
Ensembl Protein ENSMUSP00000098796
InnateDB Gene IDBG-161385 (Bst1)
Protein Structure
UniProt Annotation
Function Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth.
Subcellular Localization Cell membrane; Lipid-anchor, GPI-anchor.
Disease Associations
Tissue Specificity Expressed in the bone marrow, spleen and thymus in lymphoid organs, and the lung, kidney and heart in non- lymphoid organs.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003953 NAD+ nucleosidase activity
GO:0016740 transferase activity
GO:0050135 NAD(P)+ nucleosidase activity
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005886 plasma membrane
GO:0031225 anchored component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:105370
InterPro IPR003193 ADP-ribosyl cyclase (CD38/157)
PFAM PF02267
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q64277
PhosphoSite PhosphoSite-
TrEMBL Q3TPZ1
UniProt Splice Variant
Entrez Gene 12182
UniGene Mm.246332
RefSeq NP_033893
MGI ID
MGI Symbol Bst1
OMIM
CCDS CCDS19264
HPRD
IMGT
EMBL AC140277 AK041059 AK164028 D31788 L32812
GenPept AAA67046 BAA06597 BAC30804 BAE37594

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca