Version 5.4
Mus musculus Gene: Bst1
Summary
InnateDB Gene IDBG-161385.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bst1
Gene Name bone marrow stromal cell antigen 1
Synonyms 114/A10; A530073F09; BP-3; Bp3; Bsta1; CD157; Ly65
Species Mus musculus
Ensembl Gene ENSMUSG00000029082
Encoded Proteins
IDBP-161387
bone marrow stromal cell antigen 1
IDBP-401013
bone marrow stromal cell antigen 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000109743:
Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008]
Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33%% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:43818886-43843247
Strand Forward strand
Band B3
Transcripts
ENSMUST00000101237 ENSMUSP00000098796
ENSMUST00000118126 ENSMUSP00000113593
ENSMUST00000126976
ENSMUST00000125838
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003953 NAD+ nucleosidase activity
GO:0016740 transferase activity
GO:0050135 NAD(P)+ nucleosidase activity
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005886 plasma membrane
GO:0031225 anchored component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000109743
View Gene Order
ENSBTAG00000006156
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00760
Nicotinate and nicotinamide metabolism pathway
mmu04970
Salivary secretion pathway
mmu04972
Pancreatic secretion pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00760
Nicotinate and nicotinamide metabolism pathway
hsa04972
Pancreatic secretion pathway
hsa04970
Salivary secretion pathway
INOH
INOH website
Nicotinate Nicotinamide metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL D3Z579 Q3TPZ1
UniProt Splice Variant
Entrez Gene 12182
UniGene Mm.246332
RefSeq NM_009763
OMIM
CCDS CCDS19264
HPRD
IMGT
MGI ID MGI:105370
MGI Symbol Bst1
EMBL AC140277 AK164028
GenPept BAE37594
RNA Seq Atlas 12182

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca