Version 5.4
Mus musculus Protein: Sel1l
Summary
InnateDB Protein IDBP-161611.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sel1l
Protein Name sel-1 suppressor of lin-12-like (C. elegans)
Synonyms AW493766; mKIAA4137; Sel1h;
Species Mus musculus
Ensembl Protein ENSMUSP00000021347
InnateDB Gene IDBG-161609 (Sel1l)
Protein Structure
UniProt Annotation
Function May play a role in Notch signaling. May be involved in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin- dependent degradation of misfolded endoplasmic reticulum proteins (By similarity). {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007219 Notch signaling pathway
GO:0034976 response to endoplasmic reticulum stress
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1329016
InterPro IPR000562 Fibronectin, type II, collagen-binding
IPR006597 Sel1-like
IPR013806 Kringle-like fold
PFAM PF00040
PF08238
PRINTS
PIRSF
SMART SM00059
SM00671
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Z2G6
PhosphoSite PhosphoSite-
TrEMBL Q80YC0
UniProt Splice Variant
Entrez Gene 20338
UniGene Mm.413398
RefSeq NP_001034178
MGI ID
MGI Symbol Sel1l
OMIM
CCDS CCDS26091
HPRD
IMGT
EMBL AF063095 AK005023 AK220502 BC049959 BC057452
GenPept AAD05210 AAH49959 AAH57452 BAB23750 BAD90512

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca