InnateDB Protein
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IDBP-161625.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Stxbp1
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Protein Name
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syntaxin binding protein 1
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Synonyms
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AI317162; AI326233; MMS10-G; Ms10g; Munc-18a; Munc18-1; N-sec1; nsec1; Rb-sec1; Sxtbp1; Unc18-1; Unc18h;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000052440
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InnateDB Gene
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IDBG-161623 (Stxbp1)
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Protein Structure
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Function |
May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions (By similarity). {ECO:0000250}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Experimentally validated |
Total |
17
[view]
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Protein-Protein |
17
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
19 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:107363
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InterPro |
IPR001619
Sec1-like protein
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PFAM |
PF00995
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PRINTS |
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PIRSF |
PIRSF005715
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
O08599
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PhosphoSite |
PhosphoSite-O08599
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TrEMBL |
Z4YL99
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UniProt Splice Variant |
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Entrez Gene |
20910
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UniGene |
Mm.449636
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RefSeq |
NP_033321
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MGI ID |
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MGI Symbol |
Stxbp1
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OMIM |
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CCDS |
CCDS15933
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HPRD |
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IMGT |
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EMBL |
AB012697
AF326545
AF326563
AL772271
AL845471
BC031728
D45903
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GenPept |
AAH31728
AAL37391
AAL37409
BAA19479
BAA32486
CAM20726
CAM20727
CAM20728
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