InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Htr3a

Summary

InnateDB Protein

IDBP-162252.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Htr3a

Protein Name

5-hydroxytryptamine (serotonin) receptor 3A

Synonyms

5-HT3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000003826

InnateDB Gene

IDBG-162250 (Htr3a)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004993	serotonin receptor activity
GO:0005230	extracellular ligand-gated ion channel activity
GO:0005232	serotonin-activated cation-selective channel activity
GO:0005249	voltage-gated potassium channel activity
GO:0051378	serotonin binding

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0006812	cation transport
GO:0007210	serotonin receptor signaling pathway
GO:0042220	response to cocaine
GO:0045471	response to ethanol
GO:0071363	cellular response to growth factor stimulus
GO:0071805	potassium ion transmembrane transport

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030424	axon
GO:0043025	neuronal cell body
GO:0045211	postsynaptic membrane

Protein Structure and Domains

PDB ID

MGI:96282

InterPro

IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
IPR006201 Neurotransmitter-gated ion-channel
IPR006202 Neurotransmitter-gated ion-channel ligand-binding
IPR008132 5-hydroxytryptamine 3 receptor
IPR008133 5-hydroxytryptamine 3 receptor, A subunit

PFAM

PF02932
PF02931

PRINTS

PR00252
PR01708
PR01709

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite