InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mapkap1

Summary

InnateDB Protein

IDBP-162947.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mapkap1

Protein Name

mitogen-activated protein kinase associated protein 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000035451

InnateDB Gene

IDBG-162945 (Mapkap1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	40 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
GO:0017016	Ras GTPase binding
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
GO:0070300	phosphatidic acid binding
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding

Biological Process

GO:0046580

negative regulation of Ras protein signal transduction

Cellular Component

GO:0005794	Golgi apparatus
GO:0005886	plasma membrane

Protein Structure and Domains

PDB ID

MGI:2444554

InterPro

IPR008828 Stress-activated map kinase interacting 1

PFAM

PF05422

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A2AR15

UniProt Splice Variant

Entrez Gene

227743

UniGene

RefSeq

MGI ID

MGI Symbol

Mapkap1

OMIM

CCDS

HPRD

IMGT

EMBL

AL808102 AL845262

GenPept